Healio Rheuminations
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Healio Rheuminations
Rheumatology is an incredibly fast-moving and exciting field of medicine that can be difficult to keep up with. This Healio podcast provides busy clinicians with quick updates in the field of autoimmunity, with emphasis on new medications, treatment guidelines and explorations into the pathophysiolo...
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The Unnecessarily Complex Story of Rheumatoid Factor
The story of rheumatoid factor could be a 10 minute episode, but in this episode, we dig deep into the history of the lab techniques leading up to thi...
Don’t forget the toes: Managing patients with ANCA vasculitis
Active or not active, that is the question. In this week's episode we interview Alexandra Villa-Forte, MD, MPH, a staff physician in the Center for Va...
Healio Community Book Club: A conversation between Leonard Calabrese, DO and Eric Topol, MD, author of Super Agers
This special edition episode features the latest installment of Healio Community’s book club. Physician author Eric Topol, MD, discusses his book, Sup...
The Astounding Account of the IL-17 and Spondylarthritis
In this episode, we focus on the history of researchers discovering the clinical applicability of the IL 23/17 axis, with a particular emphasis on pso...
The Tumultuous Tale of Th17-and the IL23/IL17 immune axis
In this episode, we dive into a two-part story of intrigue starting from a paradigm shift in understanding of T cell biology because of a mouse model...
History of polymyalgia rheumatica: The origin of the pain & link to giant cell arteritis
In this episode, we dive into the history of polymyalgia rheumatica, how it was discovered and its link to giant cell arteritis.
We’d love to he...
Pulmonary hypertension, part 4: The therapeutics, with Dr. Joseph Parambil
In the final part of this series, Joseph Parambil, MD, walks us through the approach of managing pulmonary hypertension, reviews the pathophysiology a...
Pulmonary hypertension, part 3: Early therapies and vascular physiology
In this episode, we dive into the early therapies and how our understanding of vascular physiology drastically changed the management of pulmonary hyp...
Pulmonary hypertension and the rheumatologist, part 2: The history
In part 2, we dig into the history of pulmonary hypertension. How did this strange diagnosis first get recognized, what does it have to do with cows w...
Pulmonary hypertension and the rheumatologist, part 1: A bit of background
In this series, we dive into what rheumatologists should know about pulmonary hypertension, starting an interview with Joseph Parambil, MD, where we l...
COVID's role in autoimmunity and where we are in the world of long COVID
On this episode, hear the 2024 updates on COVID-19, long COVID and the latest developments in research in rheumatology. Hosted by Dr. Leonard Calabres...
The Story of the Flu Vaccine (Re-Release)
It's that time of year again, everyone rolling up their sleeves to get a flu shot. This throwback episode dives into the history of the struggles pinn...
NSAIDs, Part 3: The rise, fall and rise again of COX-2 inhibition
In the third episode of the NSAIDs saga, we focus on COX-2 inhibition! Did the hopes and dreams of selective COX-2 inhibition pan out? What can the ri...
NSAIDs, Part 2: The Dawn of the Anti-Inflammatories
In this episode, we dive into the story of aspirin and the development of ibuprofen, ending with the experiments that showed the mechanism of how aspi...
The Discovery of Non-Steroidal Anti-inflammatory Drugs (NSAIDs), Part 1
Humans have had an insatiable appetite for inhibiting production of prostaglandins for centuries! This series delves into the history of aspirin and N...
Urticarial Vasculitis, Part 2: Walking the Balance Beam of Allergy and Rheumatology
This episode digs into the pathophysiology of urticaria vasculitis from anti-C1q to the story of bradykinin.
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Urticarial Vasculitis: Attack of the Nettles, Part 1
Is it an allergy or an autoimmune vasculitis, or a little of both? Find out the story of urticarial vasculitis, how this disease was recognized and ev...
COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO
What should rheumatologists know about what we've learned about COVID-19 and long COVID in 2023? Hosted by Dr. Leonard Calabrese.
· Intro...
The Story of the Flu Vaccine
It's that time of year again, everyone rolling up their sleeves to get a flu shot. This episode dives into the history of the struggles pinning down t...
It's in the Air: Silica exposure and the risk of autoimmunity, Part 4
What is silica? How does it impact your risk of developing autoimmunity if you inhale it, inject it or even snort it up your nose? Listen and find out...
Autoimmunity, Part 3: The Lupus Gradient
In this episode, we dig through the data of lupus in Africa and speak with experts on the Lupus Gradient, the impact of malaria and what we can learn...
The Geography of Autoimmunity, Part 2
This episode delves into what we can learn about the impact of the environment on autoimmunity, digging into how rates of autoimmunity can vary drasti...
The Environment and Autoimmunity, Part 1
This episode delves into the history of the hygiene hypothesis. What do we know about different exposures changing risk for asthma and allergies, and...
An Afternoon with the Glaucomfleckens: On hypermobility and physician burnout
On this special episode of Rheuminations, I interview comedian and ophthalmologist William Flanary, MD, and Kristin Flanary, also known as the Glaucom...
The Black Death and Autoimmunity
Was your psoriasis caused by the Black Death? Learn more than you might have wanted to know about the Black Death and delve into the data on the immun...
Vascular Ehlers Danlos Syndrome for the Rheumatologist, Pt 2: Extra-Cellular Matrix Reloaded
In this episode we explore ways in which the extracellular matrix can be manipulated, including the story of doxycycline, TGF-beta in Marfan syndrome...
Vascular Ehlers-Danlos Syndrome, Part 1
Dive into vascular Ehlers-Danlos syndrome. What is it? How does it present? Get clues to its diagnosis and learn more about collagen than you ever wan...
Making Sense of Sensory Ganglionopathies, Part 2
In this episode, Dr. Benjamin Claytor walks us through his approach to suspected sensory ganglionopathies. I also cover other neurologic complications...
Making Sense of Sensory Ganglionopathies and Sjogren’s Syndrome
A sensational (or lack thereof) series on the signs and symptoms of the spellbinding sensory ganglionopathies.
Disclosures: Brown reports no rel...
Long COVID: Some facts, unanswered questions and implications for rheumatology – Part 2
In part two, Leonard Calabrese, DO, discusses the symptoms of long COVID and the role that rheumatologists play in diagnosing and treating patients wi...
Long COVID: Some facts, unanswered questions and implications for rheumatology – Part 1
In this episode, Leonard Calabrese, DO, reviews the history and controversies of post-infection sequelae, as well as the facts and epidemiology of lon...
The Story of the Synovium
How is the synovial fluid produced? Who figured it out? It’s a ripping yarn involving corpses, cats, anti-hypertensives, steroids and streptococcus.
SAPHO Part 2: An Abundance of Acronyms (AAOA)
What does the PAPA spectrum disorder teach us about SAPHO? Is SAPHO an autoinflammatory condition or part of the SpA spectrum? Why have antibiotics be...
SAPHO Part 1
What is SAPHO? What does the ‘H’ stand for, again? This episode explores some basics about the condition and delves into the history of how this disea...
The Glucocorticoid Toxicity Index with John Stone, MD, MPH
Glucocorticoids can do a lot of harm over time. In this episode, John Stone, MD, MPH, walks us through the Glucocorticoid Toxicity Index (GTI), a vali...
A Cat in Wolves' Clothing, Part 3: An ID Perspective
In this episode, Cassandra Calabrese, DO, dual-boarded in infectious disease and rheumatology, walks us through when to suspect Bartonella (it’s not a...
A Cat in Wolves' Clothing, Part 2: The History of Bartonella
Is this episode clinically relevant? No. Is it important? I think so! The story of Bartonella features a cast of characters, including a medical stude...
A Cat in Wolves’ Clothing: Bartonella and the Rheumatologist
Bartonella is an important mimic of a variety of autoimmune diseases, and it can be subtle. This episode tackles the ways in which this strange organi...
Paget's and the Rheumatologist: Why Haven't I Seen This Yet?
What is Paget’s? Why is it declining across much of the globe? Find out, plus hear an interview with the head of the center for osteoporosis and metab...
A Sickness in the Serum, Part 3: The Search for Immune Complexes
The final episode in this trilogy delves into the advancement in laboratory techniques that allowed for more accurate measurements of immune complexes...